Product Description
Carbomer 934P / 974P
Water Soluble Carbomer For Thickening, Suspending & Stabilizing
Description
CARBOMER range are synthetic high molecular weight crosslinked polymers of acrylic acid, which confirm to USP./INF. specifications as "CARBOMER"
Use
CARBOMER range, are water soluble polymer use to :
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Thicken
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To produce wide range of viscosities and flow properties.
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Suspend
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Insoluble ingredients.
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Stabilize & Emulsify
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Emulsions
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Grade & Applications
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Grades
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Solvent used in process
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Carbomer 934P / 974P
(Benzene free)
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Benzene
Cyclohexane & ethyl acetate
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Carbomer 934P / 974P - High purity oral pharmaceutical grade for formulations.
¤ Gel, Lotion and ointment.
¤ Oral liquid, suspension and emulsion.
¤ Sustained release formulation by matrix system.
¤ Opthalmic gel and eye - lotion.
¤ Transdermal (skin) drug delivery.
¤ Taste masking.
Advantages
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Thickning efficiency
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High viscosities at low concentrations.
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Uniform performance
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Reproducibility unattainable with natural gums.
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Safety
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Years of successful use of carbomers.
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Temperature stability
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Extended up to 750C heating or cooling
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Unaffected by aging
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Excellent self life.
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Microbial resistance
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Resists bacterial attack and does not support mold growth
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Versatility
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Although primarily used in aqueous systems with neutralization. It can also be used in solvent systems, with or without neutralization.
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Elegance
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Smooth and luxurious feeling.
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Chilling Properties
On refrigeration CARBOMER gel can retaining the cool temperature level for 48 hours to 72 hours. Low temperature necessary for vaccines, toxoids, insulin and human albumin can be store in pre-refrigerated CARBOMER gel, making it as a suitable medium for transporting these medicines.
Specifications
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Appearance
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White fine free flowing powder.
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Odour
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Mild acidic.
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pH of 1% solution
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2.5 to 3
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Carboxylic content
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56% to 68%
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Heavy metals
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Max. 2 ppm
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Temperature stability
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Up to 75°C
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Grades
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Grades
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Viscosity (20°C, 0.5% Neutralization)
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Carbomer 934P / 974P
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29,400 - 39,400 cps.
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Preparation of Aqueous Transparent Gel
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D.M. water
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97.0 gm.
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Carbomer (Any Grade)
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0.5 gm.
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Sodium Hyroxide
(10% solution)
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2.5 gm.
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Neutralizers Recommended
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Sodium Hydroxide
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Potassium Hydroxide
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Triethanol Amine
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Triethyl amine, other alkalies etc..
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Toxicity
CARBOMER is a high molecular weight polymer. It is not absorbed by body tissues and is totally safe for human oral consumption. Test for toxicological tolerance show that it does not have pronounced physiological action and is non toxic.
Storage
Store in cool dry place. Keep away from moisture and water.
Packing
5 kg., 20 kg., net in corrugated box.
Certificate of Analysis ( CARBOMER - 974P )
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No.
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Test
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Specification
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Results
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1
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Description
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White Free Flowing Powder
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White Free Flowing Powder
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2
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Solubility
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Complies
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Alkali Water
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3
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Identification
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A. Complies
B. Complies
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Complies
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4
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Viscosity
(0.5% Solution)
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Bet'n 29400 To 39400 Cps
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36200 Cps
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5
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Loss on Drying
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NMT 2.0%
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1.2%
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6
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Heavy Metals
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NMT 0.002%
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Complies
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7
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Assay For Carboxylic Acid Content
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Bet'n 56.0% To 68.0%
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59.8%
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Certificate of Analysis ( CARBOMER - 934P )
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No.
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Test
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Specification
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Results
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1
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Description
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White Free Flowing Powder
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White Free Flowing Powder
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2
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Solubility
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Complies
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Alkali Water
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3
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Identification
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A. Complies
B. Complies
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Complies
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|
4
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Viscosity
(0.5% Solution)
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Bet'n 29400 To 39400 Cps
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38850 Cps
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5
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Loss on Drying
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NMT 2.0%
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0.9%
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6
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Heavy Metals
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NMT 0.002%
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Complies
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7
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Limit Of Benzene (By Gc)
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NMT 0.01%
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0.0021%
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8
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Organic Volatile Impurities
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Complies
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Complies
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9
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Assay For Carboxylic Acid Content
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Bet'n 56.0% To 68.0%
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59.9%
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